Wine is an Open Source implementation of the Windows API on top of X, OpenGL, and Unix.
Think of Wine as a compatibility layer for running Windows programs. Wine does not require Microsoft Windows, as it is a completely free alternative implementation of the Windows API consisting of 100% non-Microsoft code, however Wine can optionally use native Windows DLLs if they are available. Wine provides both a development toolkit for porting Windows source code to Unix as well as a program loader, allowing many unmodified Windows programs to run on x86-based Unixes, including Linux, FreeBSD, Mac OS X, and Solaris. For more... http://www.winehq.org/
One way of installing wine: using linux command prompt (root access)
1. #yum install wine* it will then install wine and all its required libraries
2. Wine has its own C:/ directory and program files to keep your installed software under
Menu > Wine > Wine File
Then, I followed the documentation on the site for configuring wine. http://www.winehq.org/docs/en/wineusr-guide.html#CONFIG-WINE-MAIN
see wine website for other detailed info.